Role at National Level

ICARS will contribute to national efforts to tackle antimicrobial resistance by partnering with low- and middle-income countries to conduct intervention and implementation research.

ICARS will:

  • Provide support to low- and middle-income countries in translating policies and One Health national action plans into practice,
  • Build on existing research and international development efforts while expanding the scale and scope of the response and
  • Increase investment and collaboration across sectors. 

What ICARS will do

Upon request from low- and middle-income countries, ICARS will work closely with national and local stakeholders to identify priorities and to develop evidence based, context-specific and cost-effective solutions to mitigate antimicrobial resistance in low- and middle-income countries. 

Where information and solutions exist, ICARS will conduct research to identify the root causes inhibiting implementation and develop cost-effective and context-specific solutions to overcome the challenges.

In areas where little is known about what interventions and solutions work most effectively, in what contexts, and what should be prioritised, ICARS will determine their relative importance and interdependency across different sectors and contexts and conduct cost-benefit analyses.

How ICARS will Operate

Based on a governments request and a commitment to act, ICARS will work with the country’s Antimicrobial Resistance Coordinating Committees and other stakeholders, to identify and prioritize activities using global and national action plans as the foundation. When developing specific projects and solutions, ICARS will take a participatory research approach and work with national and local policymakers, academics, professionals, businesses, communities, and wider stakeholders (the Tripartite, UNEP, NGOs, developing programs etc.) as appropriate.  

By close consultation, collaboration and alignment with existing activities, ICARS will avoid duplication, build on, and strengthen the essential wider efforts to address antimicrobial resistance within the country. 

ICARS will utilise existing expertise within the country and build further capacity and capability so efforts can be sustained and scaled up at national and international levels. Projects will include economic evaluations to inform of the cost-benefit of the identified solutions. Projects can be executed by ICARS internally or can be commissioned.

Projects will be regularly reviewed, adapted, and evaluated throughout the project and after completion. The knowledge, evidence, and solutions identified will feed into ICARS global communication work and aim to be on open access repositories (new and existing). 

When considering activities and engagement, ICARS will take into account: 

  • Political, policy and technical engagement at all levels including willingness to uptake and sustain identified value adding solutions
  • Evidence from the government that they wish to address antimicrobial resistance through a One Health approach
  • Existing human resources and research infrastructure to co-execute the research projects
  • Alignment with other global and national initiatives.
An example of a process that ICARS will take to implement projects at national and local levels in low- and middle-income countries includes the following steps:


10 steps

Examples of Potential Areas of Activity